SINCLAIR GINZA CLINIC

Ginza, Tokyo

Over the 20 years, successfully conducted 100,000 stem cell cultivations without any incidents.
We perform treatments using products manufactured by "Ainprose" in this cultivation and processing facility.

About "Ainprose"

Ainprose (:anti-inflammatory products from stem cell) contains over 2,000 types of physiologically active substances, including endogenous bio-nanoparticles, which are believed to promote tissue regeneration by influencing cells. Expectations for its effectiveness of this therapy are high.

Expected Benefits of Ainprose

Vascular regeneration and angiogenesis.

Collateral angiogenesis for interrupted blood circulation due to atherosclerosis.

Nerve cell repair and regeneration.

Repair of peripheral nerves.

Anti-inflammation effects.

Promotes healing of damaged areas (injuries and inflammations) and reduces pain.

Anti-oxidant effects.

Recovery from fatigue, prevention of lifestyle diseases.

Immune system regulation.

Improvement in allergies and sensitivities.

Cosmetic Effects.

Anti-wrinkle and sagging treatment with tissue repairing.

Symptoms observed with the use of Ainprose in adjunctive therapy.

Bone, Muscle, Joint

Gout
Hernia
General stiffness
Frozen shoulders
Strained back
Bone fractures
Torn muscles
Heberden's nodes
Wrist tendonitis

Systemic symptoms

Headaches
Brain fog
Fatigue
Dizziness
Insomnia / night sweats
Chronic pain
Rheumatic diseases
Promote wound healing
Improve post-op after effects
Poor immunity
Swelling
Hangovers

Neurological symptoms

Numbness
Motor paralysis
Sensory abnormalities
Diabetic neuropathy
Dementia

Vascular symptoms

Arrhythmia
Peripheral circulation disorders
Arteriosclerosis
Myocardial infarction
Cerebral infraction

Liver pancreas symptoms

Dyslipidemia
High blood sugar

Respiratory symptoms

Pneumonia
Asthma

Vision symptoms

Eye strain
Impaired vision
Presbyopia
Floaters
Diabetic retinopathy

Urological symptoms

Frequent urination
Urinary incontinence
Erectile dysfunction (ED)

Skin

Rough skin
Vitiligo
Rashes
Burn scars

Gynecological symptoms

Infertility
Menopausal disorder

Expected Effects of Growth Factors in Ainprose

EGF	EGF (Epidermal Growth Factor) is composed of amino acids that promote the production of new cells, which can act on various cells to encourage growth of cells, regulate proliferation, and make repairs.
VEGF	VEGF (Vascular Endothelial Growth Factor) plays a key role in angiogenesis and induce cell division and differentiation, which causes the formation of new blood vessels that branch off from existing ones.
TGF-β	TGF-β (Transforming Growth Factor) regulates cell proliferation, growth, differentiation, and motility, playing key roles in the reconstruction, wound healing, and immunity of cellular tissues.
HGF	HGF (Hepatocyte Growth Factor) promotes the proliferation of hepatocytes involved in the synthesis and storage of proteins, the conversion of carbohydrates, and the detoxification, denaturation, and elimination of cholesterol and xenobiotics.
KGF	KGF (Keratinocyte Growth Factor) is mitogenic ( induce cell division) with angiogenesis and wound healing effects, which assist in the production of keratin, an essential ingredient the formation of hair and skin.
IGF	IGF (Insulin Growth Factor) is produced by growth hormone which is secreted in large quantities during puberty. They function in a variety of ways, including the promotion of cell proliferation/differentiation, and protein assimilation.
PDGF	PDGF (Platelet-Derived Growth Factor) is produced by various cells such as epithelial and endothelial cells. They are involved in regulating the migration and proliferation of mesenchymal cells, which helps promote the growth and regeneration of damaged tissues.
FGF	FGF (Fibroblast Growth Factor) is involved in angiogenesis and wound healing. They play key roles in the proliferation and differentiation of wide range of cells and tissues.
IL-7	IL-7 (Interleukin-7) is bioactive substances that promote cell proliferation, and is keys to the survival, proliferation and maturation of cells.
GM-CSF	GM-CSF (Granulocyte-Monocyte Colony-Stimulating Factor) promotes cell survival and activation. They are hematopoietic growth factors that promote the differentiation into pluripotent hematopoietic stem cells and function as immunoregulatory factors.
EPO	EPO (Erythropoietin) is mainly produced in the kidneys, and are one of the hematopoietic factors that promote the production of red blood cells.
TSG-6	TSG-6 (Anti-Inflammatory Factor) is gaining attention for suppressing inflammation, and as a treatment for arteriosclerosis.
TPO	TPO (Thrombopoietin) is involved in the proliferation and differentiation of pro-platelets, and are considered to be key factors in the production of hematopoietic cells.
TIMP	TIMP (Tissue Inhibitor of Metalloproteinase) inhabits the degradation of tissue collagen and elastin by MMPs, and helps prevent fibrosis.

Six Functions of Ainprose

Awakens Stem Cells.

Awakens the original function of stem cells inside the body, help to proliferate the surrounding stem cells, and promote differentiation into needed cells.

Suppresses Inflammation.

Suppresses various sources if inflammation, including inflammation due to the break down tissue and organs, to help relieve intense pain and impaired movement.

Improves Metabolism.

Breaks down harmful proteins inside the body, including the blood and the circulatory system, improves glucose metabolism, and reduces hyperlipidemia.

Regenerates Blood Vessels.

Regenerates blood vessels to supply more essential resources like oxygen and nutrients to tissues and organs, which restores the whole body.

Improves Immunity.

Maintains the balance of immune system functions by promoting activation and regulation of immune cells.

Stimulates the Brain.

Boosts communication between cells to help prevent decline in cognitive function and activate the brain.

The difference from stem cell therapy

Stem cell therapy involves harvesting a patient's own stem cells, culturing and proliferating them, and reintroducing them into the body to facilitate tissue regeneration and treat diseases.

On the other hand, AINPROS® utilizes endogenous bio-particles and bioactive substances secreted from stem cells. Unlike direct transplantation of stem cells, AINPROS® works by harnessing these components to promote tissue regeneration. Its distinctive feature lies in this approach, which eliminates the need for cell extraction, resulting in minimal invasiveness. Additionally, there is no waiting period for cell culturing, offering another advantage.

Prices

Those who do NOT have a Japanese health insurance.

AINPROS® 30ml: 1 treatment Intravenous infusion	671,000 JPY (including tax)
AINPROS® 30ml: 3 treatments Intravenous infusion + [Re:A set of 4 cosmetics] + [NMN supplement]	2,013,000 JPY (including tax)
AINPROS® 30ml: 6treatments (+1) Intravenous infusion + [Re:A set of 4 cosmetics] + [NMN supplement]	4,026,000 JPY (including tax)
AINPROS® 10ml: 1 treatment Intravenous infusion	308,000 JPY (including tax)
AINPROS® 5ml: 1 treatment Intra-articular injection	170,500 JPY (including tax)
AINPROS® treatment: 1 body part Intra-articular injection	134,200 JPY (including tax)
AINPROS® 2ml Ultrasonic Penetration	86,900 JPY (including tax)
AINPROS® 1ml Ultrasonic Penetration	64,900 JPY (including tax)

※If you receive consultation without treatment, a consultation fee will be charged. ( visiting fee/¥16,600 + consultation fee per additional 15min/¥5,500)
※One of the risks associated with this therapy is that the administration of the stem cell culture supernatant may cause side effects such as temporary allergies.
※Stem cell culture supernatant is not a pharmaceutical product approved under the PMD Act.
※In Japan and other countries, there is no definitive information on the potential for serious risks associated with stem cell culture supernatant.
※There is no other approved pharmaceutical product in Japan with the same ingredients and functions as stem cell culture supernatant.

Clinic Information

Name of Medical Institution	General Incorporated Association Advalife Science SINCLAIR GINZA
Address	FPG links GINZA 4F, 5F 2-8-19 Ginza, Chuo-ku, Tokyo-to, Japan
Nearest Station	Ginza-itchome, Ginza, Higashi-ginza, Yurakucho(JR)
Operation Hours	10:00-13:00 / 14:00-19:00
Website	https://s-gc.jp/eng/

Over the 20 years, successfully conducted 100,000 stem cell cultivations without any incidents.We perform treatments using products manufactured by "Ainprose" in this cultivation and processing facility.